_____ his knowledge of the mountainous country, John Smith was appointed as our guide.
| A．In spite of | B．On account of |
| C．Regardless of | D．Instead of |
—Jenny,I think I’ll just have some coffee for a change.
—___________.The coffee I bought yesterday is in the cupboard.
| A．Change it,please | B．Never mind |
| C．With pleasure | D．Help yourself |
—I really thought I’d win the game.
—Oh,well, ___________,Bill.
| A．no problem | B．better luck next time |
| C．best wishes | D．take your time |
—I’d like to take a chance and run a business.
—Do you know about the local market? ___________.
| A．No problem | B．Better play it safe |
| C．Do as you please | D．Think nothing of it |
—Excuse me,do you have the time?
—Sorry,I have no watch.
—___________
| A．What a shame. | B．Thanks anyway. |
| C．It doesn’t matter. | D．Why not buy one? |
—___________?Kate,you look pale.
—Oh,thank you,it doesn’t matter.
| A．What’s on | B．What’s up |
| C．Are you ill | D．Do you feel terrible |