Great changes ____________ in my hometown in the past few years.
| A．took place | B．have taken place | C．have been happened | D．broke out |
I lost my way in complete darkness and, _____matters worse, it began to rain.
| A．made | B．having made | C．making | D．to make |
_________she couldn't understand was_______fewer and fewer students showed interest in her lessons.
| A．What; why | B．That ; what | C．What ; because | D．What;what |
The queen will visit the town in May, _____she will open the new hospital.
| A．when | B．then | C．while | D．but |
Lu Xun was ___________ medical student before he turned ___________ great writer.
| A．the; the | B．the; a | C．a; / | D．a; a |
Many people have been ill from a strange disease these days,_________we’ve never heard of before.
| A．one | B．that | C．it | D．this |