Chinese scientists have found a new way to use cells found in human urine （尿液）that could aid in the treatment of a range of nerve disorders.That is a new technique for reprogramming cells in human urine into nerve progenitor cells that can grow into multi-functional nerve and brain cells.
The technique is expected to be used in the study and treatment of nerve disorders such as Parkinson's disease, Alzheimer's disease and other nerve disorders.
Pei Duanqing, a professor at Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, said his research team has combined an episomal system to deliver reprogramming factors with a chemically defined culture medium to reprogram kidney epithelial(肾表皮) cells in urine into NPCs.
These NPCs, normally only found in the human brain, were later proven to be transgene-free and self-renewing, he said.
"These nerve and brain cells can survive for up to one month when transplanted into the brain of a newborn rat," said Pei. "My team is working hard to understand why our experimental condition allowed the urine cells to become NPCs, because we want to improve the technique and make it more efficient".
Scientists have long searched to treat and study neural disorders by obtaining and transplanting neural stem cells. However, the previous method of getting and using cells from either fetal (胎儿)or adult human tissue remains challenging due to ethical concerns and immune system rejections, he said.
Pei hopes the discovery will be used to generate NPCs from patients with nerve disorders such as Parkinson's disease. "These NPCs from patients may help us discover new drugs for these diseases."
"It is a remarkable advance in the stem cell field. The results and methods obtained from this study will be of great value and significance to the field, " said Fred Gage,a professor with the Salk Institute for Biological Studies.What is the passage mainly about?
| A．NPCs are beneficial in treating human diseases. |
| B．Chinese scientists succeeded in making NPCs from human urine. |
| C．Chinese scientists have found cures for all diseases. |
| D．A new technique was used to study the use of human urine |
Pei and his team try their best to work hard in order to .
| A．make more contributions to medical study |
| B．discover another new technique |
| C．make the technique more perfect |
| D．treat more patients suffering from bad diseases |
What is the challenge of making NPCs in the previous method?
| A．The ethical concerns and immune system refusal |
| B．The difficulties in getting cells from human. |
| C．The under-developed techniques in medical science. |
| D．The lack of financial support from the government |
From the last paragraph we can infer .
| A．the new technique will be developed in science |
| B．the result and methods will be applied to treating cancers |
| C．the study will give a major push to the stem cell field |
| D．the new technique will bring great profits |
Last week I was riding my special motorbike and then stopped at a convenience store. As I was getting my wheelchair off the back, a man watched me from his car and I noticed a wheelchair in his back seat. We spoke for a moment and I asked him about the wheelchair. He answered that it was for his daughter. “Well, do you think she would like to go for a ride on my motorbike with me?” I asked. He seemed shocked that a total stranger would ask him this. He thought about it for a second and said, “OK, as long as I can follow you.”
He introduced me to Amy and he sat her on my back seat. Her father followed me for a few miles and she talked non-stop about what she wanted for Christmas. As we came back to the convenience store, she said, “This ride is the best Christmas present I could ever receive. I have been in a wheelchair my whole life and didn't know I could do this.” I told her about some of the other things I do (ski, travel the world by myself, etc.). As her father was taking her off my bike, she turned to him and said, “Oh Daddy, I'm going to be OK. Mr. Bryant does all kinds of things, and I will too.” Her father turned away as a tear of joy rolled down his cheek. He hugged me and said, “I was sitting here praying for a gift for Amy that would encourage her. She often felt that her life was dull compared to other children. God answered my prayer just now. Now I pray that God will bless you for your gift to Amy today.” I believed what he said. Being kind and thoughtful to others, we can be an answer to prayer.How did the father feel at first when the author invited his daughter for a ride?
| A．He was happy because his daughter could gain excitement. |
| B．He was moved because the author offered to help his daughter. |
| C．He felt surprised because he didn’t know the author. |
| D．He felt nervous because he was worried about his daughter's safety. |
According to the passage, the girl ____________.
| A．used to be a completely healthy person |
| B．was inspired by the author's experiences |
| C．was satisfied with her life |
| D．was unwilling to communicate with a stranger |
What was the author's gift to Amy according to the girl's father?
| A．The motorbike | B．The wheelchair |
| C．The blessing | D．The ride |
What can we infer from the passage?
| A．The author usually drove too fast |
| B．The author worked in a convenience store |
| C．The author often offered strangers a ride on his motorbike |
| D．The author was a man with disability |
For one tired out from work, autumn is one of the best times to step into the open air to kick back and enjoy some great music. And that’s what many Beijingers have done this past weekend.
Family, friends, laughter; beautiful grass, fresh air and live music echoing (回响) off the forest and the Great Wall that surround this place. A weekend in this music paradise（乐园） just seems too short. Besides, a brand new world-class outdoor theater has just been open at this year’s festival, which will surely make the festival a better and more permanent experience.
A full house is before the new outdoor amphitheater (圆形剧场). Even the thunderstorm couldn’t break up the crowd completely absorbed in the music. Thanks to the new theater, this year’s Great Wall Forest Festival offers even more superb acoustics（音效的）and an overall outdoor theatrical experience, even though the project is still half complete.
The festival is now in its fourth year. Since its first show in 2010, the festival has seen a steady increase in festival-goers and has expanded its length from two days to four days, divided over two weekends. It has also been experimenting with a variety of styles, from classical to pop, with this year’s theme “Celebrating 20 Years of Chinese Folk Song.” Folk Song legend Lao Lang explains how folk songs have helped encourage more amateur folks to express themselves through music.
“Before music was reserved for the professionals. But folk songs made young people realize that they can express themselves through music as well. And that’s what characterizes folk songs. It’s popular music and it always has a story.” said Lao Lang.
Unlike some of the other outdoor festivals, the Great Wall Forest Festival appeals to a wide range of audiences. It’s a rare place where teens, parents and families can all enjoy the outdoors and have a great time.
Great music and scenery aside, many children’s workshops, master music classes, and interactive art activities have also been introduced this year. If music is the reason to come to the festivals, you’ll find even more reasons not to leave.What is the meaning of the underlined phrase “kick back” in Paragraph 1?
| A．to hit with legs. | B．to work harder |
| C．to relax oneself | D．to make people leave |
Which of the following is NOT true?
| A．The place where the Festival is held is near the Great Wall. |
| B．The completed project adds to the attraction of this year’s Festival. |
| C．The audience attending the festival bury themselves in the music. |
| D．The year 2010 saw the beginning of the Great Wall Forest Festival. |
The 2014 Great Wall Forest Festival has got improved in the following aspects except that _________.
| A．it has included different types of music |
| B．it has attracted a wide range of audiences |
| C．it has introduced more activities besides music |
| D．it has been expanded from 2 days to 4 days in a week |
According to Lao Lang, we can know that _________.
| A．folk songs can help amateur singers become famous easily |
| B．folk songs are the ones just intended for the professionals |
| C．a folk song, always with a story, belongs to popular music |
| D．popular songs are used by the young to express themselves |
Holidaymakers who are bored with baking beaches and overheated hotel rooms head for a big igloo. Swedish businessman Nile Bergqvist is delighted with his new hotel, the world’s first igloo hotel. Built in a small town in Lapland, it has been attracting lots of visitors, but soon the fun will be over.
In two weeks’ time Bergqvist’s ice creation(作品) will be nothing more than a pool of water. “We don’t see it as a big problem,” he says. “We just look forward to replacing it.”"
Bergqvist built his first igloo in 1991 for an art exhibition. It was so successful that he designed the present one, which measures roughly 200 square meters. Six workmen spent more than eight weeks piling 1,000 tons of snow onto a wooden base; when the snow froze, the base was removed. “The only wooden thing we have left in the igloo is the front door,” he says.
After their stay, all visitors receive a survival certificate recording their success. With no windows, nowhere to hang clothes and temperatures below 0℃, it may seem more like a survival test than a relaxing hotel break. “It’s great fun,” Bergqvist explains, “as well as a good start in survival training.”
The popularity of the igloo is beyond doubt: it is now attracting tourists from all over the world. At least 800 people have stayed at the igloo this season even though there are only 10 rooms. “You can get a lot of people in,” explains Bergqvist. “The beds are three meters wide by two meters long, and can fit at least four at one time.”Bergqvist designed and built the world’s first igloo hotel because _________.
| A．more hotel rooms were needed |
| B．he wanted to make a name for the small town |
| C．an art exhibition was about to open |
| D．he believed people would enjoy trying something new |
When the writer says “the fun will be over,” he refers to the fact that _________.
| A．hotel guests will be frightened at the thought of the hard test |
| B．holidaymakers will soon get tired of the big igloo |
| C．Bergqvist’s hotel will soon become a pool of water |
| D．a bigger igloo will replace the present one |
When guests leave the igloo hotel they will receive a paper stating that _________.
| A．they have visited Lapland |
| B．they have had great fun sleeping on ice |
| C．they have had a taste of adventure |
| D．they have had an ice-snow holiday |
Which of the four pictures below is the closest to the igloo hotel as described in the text?
| My Left Foot (1989) Imagine being a prisoner of your own body, unable to make any movements except to move your left foot. The main character in My Left Foot，based on the real story of cerebral palsy (大脑性麻痹) sufferer Christy Brown, can barely move his mouth to speak, but by controlling his left foot, he’s able to express himself as an artist and poet. For his moving performance of Brown, Daniel Lewis won his first Academy Award for best actor. |
 |
| Shine (1996) Do you have a talent you’re afraid to share with the world? David Helfgott seemed meant from childhood to be “one of the truly great pianists,” but the pressures of performing (and pleasing his father) resulted in a complete breakdown. Ten years in a mental institution didn’t weaken Helfgott’s musical gift: When he was rediscovered, he was playing concertos in a bar. Shine received seven Oscar nominations (提名), and Geoffrey Rush won best actor for his performance of Helfgott. |
 |
| Life Is Beautiful (1997) Nothing’s more powerful than the love between a parent and a child. In this heartbreaking Italian film, a father (Roberto Benigni) makes an unbelievable sacrifice for his 4-year-old son: trapped in a Nazi concentration camp in 1945, the Jewish man convinces his boy that they are playing a complicated game. He manages to spare him the horror of the terrible war, and even in his final moments of life, keeps his son smiling and hopeful. Benigni won the best actor Oscar. |
 |
| Stand and Deliver (1988) Few people can inspire us more than a good teacher. Jaime Escalante (Edward James Olmos got Oscar nomination for best actor) is a great one. Employed at a high school where kids are expected to fail, Escalante challenges his math students to struggle for better things, like getting good grades in the AP exam. Despite the obstacles in their lives, the classmates accomplish their goals, thanks to Mr. Escalante’s support. The real Jaime Escalanteis, the Best Teacher in America, says that Stand and Deliver is “90% truth, 10% drama.” |
 |
The underlined part in the passage means _________.
| A．The main character in My Left Foot is a prisoner |
| B．The main character in My Left Foot is trapped by others |
| C．The main character in My Left Foot is a disabled person |
| D．The main character in My Left Foot can’t control his whole body |
If you want to watch a movie about wars, which may be one of your choices?
| A．My Left Foot. | B．Shine. |
| C．Life Is Beautiful. | D．Stand and Deliver. |
Jaime Escalante has a talent for _________.
| A．teaching | B．drawing and writing |
| C．making stories | D．playing the piano |
What do the four movies have in common?
| A．They are all based on real stories. |
| B．They are all inspiring stories that make a difference. |
| C．The main characters all won Academy Award for Best Actor. |
| D．The main characters are all sick to some degree but succeed. |
July 21st. 2007 was a typical English summer’s day—it rained for 24 hours! As usual, I rushed home from work at midday to check on the house. Nothing was amiss. By the time I left work at 5p.m., however, the road into our village was flooded. Our house had never been flooded but, as I opened the front door, a wave of waters greeted me. Thank God! The kids weren’t with me, because the house was 5 feet deep in water. We lost everything downstairs. And the plaster had to be torn off the wall’s ceilings pulled down.
At first we tried to push on through. We didn’t want to move the children out of home. So we camped upstairs. We put a sheet of plastic across the floor to protect us from the damp. But after three months, we felt very sick, so we move to a wooden house in a park. The house was small, but at first we were all just delighted to be in a new place. Unfortunately, things took longer than expected and we were there for 10 months. The life there was inconvenient. What surprised me most was how much I missed being part of a community（社区）. We had lived in a friendly village with good neighbors, and I’d never thought how much I’d miss that.
Although our situation was very bad, it’s difficult to feel too sorry for yourself when you look at what’s happening elsewhere. I watched a news report about floods in Northern India and thought. “We didn’t have a straw hut（茅草房）that was for Christmas. But I can’t wait—I’m going to throw a party for our friends in the village to say thanks for their support. This year, I won’t need any gifts—living away from home for months has made me realize how little we actually need or miss all our possessions. Although we are replacing things, there’s really no rush—we have our home back. And that’s the main thing.What does the underlined word “amiss” in the first paragraph mean?
| A．Found. | B．Missing. | C．Right. | D．Wrong. |
It can be inferred from the text that the author _________.
| A．cared much about her children |
| B．was sick of staying upstairs alone |
| C．could not stand living in a wooden house |
| D．did not deal well with her family affairs during the flood |
Why does the author say that they were lucky in the third paragraph?
| A．Because her situation was not serious. |
| B．Because some others suffered even more. |
| C．Because she had ever been to Northern India. |
| D．Because very few other places were also flooded. |
What does the author mainly want to express by telling her story?
| A．She realized she needed no more possession. |
| B．She valued human feelings more than before. |
| C．She found Christmas gifts no longer badly needed. |
| D．She thought her own home was the most important of all. |